Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis.
Identifieur interne : 001123 ( Main/Exploration ); précédent : 001122; suivant : 001124Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis.
Auteurs : Edward K. Thomsen [Papouasie-Nouvelle-Guinée] ; Nelly Sanuku [Papouasie-Nouvelle-Guinée] ; Manasseh Baea [Papouasie-Nouvelle-Guinée] ; Samson Satofan [Papouasie-Nouvelle-Guinée] ; Elit Maki [Papouasie-Nouvelle-Guinée] ; Bart Lombore [Papouasie-Nouvelle-Guinée] ; Mark S. Schmidt [États-Unis] ; Peter M. Siba [Papouasie-Nouvelle-Guinée] ; Gary J. Weil [États-Unis] ; James W. Kazura [États-Unis] ; Lawrence L. Fleckenstein [États-Unis] ; Christopher L. King [États-Unis]Source :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2016.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Albendazole (administration et posologie), Albendazole (effets indésirables), Albendazole (pharmacocinétique), Animaux, Diéthylcarbamazine (administration et posologie), Diéthylcarbamazine (effets indésirables), Diéthylcarbamazine (pharmacocinétique), Effets secondaires indésirables des médicaments (anatomopathologie), Femelle, Filaricides (administration et posologie), Filaricides (effets indésirables), Filaricides (pharmacocinétique), Filariose lymphatique (traitement médicamenteux), Humains, Ivermectine (administration et posologie), Ivermectine (effets indésirables), Ivermectine (pharmacocinétique), Jeune adulte, Mâle, Méthode en simple aveugle, Papouasie - Nouvelle-Guinée, Parasitémie (traitement médicamenteux), Projets pilotes, Résultat thérapeutique, Sérum (), Wuchereria bancrofti (isolement et purification).
- MESH :
- administration et posologie : Albendazole, Diéthylcarbamazine, Filaricides, Ivermectine.
- anatomopathologie : Effets secondaires indésirables des médicaments.
- effets indésirables : Albendazole, Diéthylcarbamazine, Filaricides, Ivermectine.
- isolement et purification : Wuchereria bancrofti.
- pharmacocinétique : Albendazole, Diéthylcarbamazine, Filaricides, Ivermectine.
- traitement médicamenteux : Filariose lymphatique, Parasitémie.
- Adulte, Adulte d'âge moyen, Animaux, Femelle, Humains, Jeune adulte, Mâle, Méthode en simple aveugle, Papouasie - Nouvelle-Guinée, Projets pilotes, Résultat thérapeutique, Sérum.
English descriptors
- KwdEn :
- Adult, Albendazole (administration & dosage), Albendazole (adverse effects), Albendazole (pharmacokinetics), Animals, Diethylcarbamazine (administration & dosage), Diethylcarbamazine (adverse effects), Diethylcarbamazine (pharmacokinetics), Drug-Related Side Effects and Adverse Reactions (pathology), Elephantiasis, Filarial (drug therapy), Female, Filaricides (administration & dosage), Filaricides (adverse effects), Filaricides (pharmacokinetics), Humans, Ivermectin (administration & dosage), Ivermectin (adverse effects), Ivermectin (pharmacokinetics), Male, Middle Aged, Papua New Guinea, Parasitemia (drug therapy), Pilot Projects, Serum (chemistry), Single-Blind Method, Treatment Outcome, Wuchereria bancrofti (isolation & purification), Young Adult.
- MESH :
- chemical , administration & dosage : Albendazole, Diethylcarbamazine, Filaricides, Ivermectin.
- chemical , adverse effects : Albendazole, Diethylcarbamazine, Filaricides, Ivermectin.
- chemical , pharmacokinetics : Albendazole, Diethylcarbamazine, Filaricides, Ivermectin.
- chemistry : Serum.
- drug therapy : Elephantiasis, Filarial, Parasitemia.
- isolation & purification : Wuchereria bancrofti.
- pathology : Drug-Related Side Effects and Adverse Reactions.
- Adult, Animals, Female, Humans, Male, Middle Aged, Papua New Guinea, Pilot Projects, Single-Blind Method, Treatment Outcome, Young Adult.
Abstract
Available treatments for lymphatic filariasis (LF) are limited in their longterm clearance of microfilaria from the blood. The safety and efficacy of a single-dose triple-drug therapy of the antifilarial drugs diethylcarbamazine (DEC), ivermectin (IVM), and albendazole (ALB) for LF are unknown.
DOI: 10.1093/cid/civ882
PubMed: 26486704
Affiliations:
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Thomsen</name><affiliation wicri:level="1"><nlm:affiliation>Papua New Guinea Institute of Medical Research, Papua New Guinea.</nlm:affiliation><country xml:lang="fr">Papouasie-Nouvelle-Guinée</country><wicri:regionArea>Papua New Guinea Institute of Medical Research</wicri:regionArea></affiliation></author><author><name sortKey="Sanuku, Nelly" sort="Sanuku, Nelly" uniqKey="Sanuku N" first="Nelly" last="Sanuku">Nelly Sanuku</name><affiliation wicri:level="1"><nlm:affiliation>Papua New Guinea Institute of Medical Research, Papua New Guinea.</nlm:affiliation><country xml:lang="fr">Papouasie-Nouvelle-Guinée</country><wicri:regionArea>Papua New Guinea Institute of Medical Research</wicri:regionArea></affiliation></author><author><name sortKey="Baea, Manasseh" sort="Baea, Manasseh" uniqKey="Baea M" first="Manasseh" last="Baea">Manasseh Baea</name><affiliation wicri:level="1"><nlm:affiliation>Papua New Guinea Institute of Medical Research, Papua New Guinea.</nlm:affiliation><country xml:lang="fr">Papouasie-Nouvelle-Guinée</country><wicri:regionArea>Papua New Guinea Institute of Medical Research</wicri:regionArea></affiliation></author><author><name sortKey="Satofan, Samson" sort="Satofan, Samson" uniqKey="Satofan S" first="Samson" last="Satofan">Samson Satofan</name><affiliation wicri:level="1"><nlm:affiliation>Papua New Guinea Institute of Medical Research, Papua New Guinea.</nlm:affiliation><country xml:lang="fr">Papouasie-Nouvelle-Guinée</country><wicri:regionArea>Papua New Guinea Institute of Medical Research</wicri:regionArea></affiliation></author><author><name sortKey="Maki, Elit" sort="Maki, Elit" uniqKey="Maki E" first="Elit" last="Maki">Elit Maki</name><affiliation wicri:level="1"><nlm:affiliation>Papua New Guinea Institute of Medical Research, Papua New Guinea.</nlm:affiliation><country xml:lang="fr">Papouasie-Nouvelle-Guinée</country><wicri:regionArea>Papua New Guinea Institute of Medical Research</wicri:regionArea></affiliation></author><author><name sortKey="Lombore, Bart" sort="Lombore, Bart" uniqKey="Lombore B" first="Bart" last="Lombore">Bart Lombore</name><affiliation wicri:level="1"><nlm:affiliation>Papua New Guinea Institute of Medical Research, Papua New Guinea.</nlm:affiliation><country xml:lang="fr">Papouasie-Nouvelle-Guinée</country><wicri:regionArea>Papua New Guinea Institute of Medical Research</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, Mark S" sort="Schmidt, Mark S" uniqKey="Schmidt M" first="Mark S" last="Schmidt">Mark S. Schmidt</name><affiliation wicri:level="4"><nlm:affiliation>Department of Pharmaceutical Sciences & Experimental Therapeutics, University of Iowa, Iowa City.</nlm:affiliation><orgName type="university">Université de l'Iowa</orgName><country>États-Unis</country><placeName><settlement type="city">Iowa City</settlement><region type="state">Iowa</region></placeName></affiliation></author><author><name sortKey="Siba, Peter M" sort="Siba, Peter M" uniqKey="Siba P" first="Peter M" last="Siba">Peter M. Siba</name><affiliation wicri:level="1"><nlm:affiliation>Papua New Guinea Institute of Medical Research, Papua New Guinea.</nlm:affiliation><country xml:lang="fr">Papouasie-Nouvelle-Guinée</country><wicri:regionArea>Papua New Guinea Institute of Medical Research</wicri:regionArea></affiliation></author><author><name sortKey="Weil, Gary J" sort="Weil, Gary J" uniqKey="Weil G" first="Gary J" last="Weil">Gary J. Weil</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Infectious Diseases Division, Washington University School of Medicine, St. Louis, Missouri.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Department of Medicine, Infectious Diseases Division, Washington University School of Medicine, St. Louis</wicri:cityArea></affiliation></author><author><name sortKey="Kazura, James W" sort="Kazura, James W" uniqKey="Kazura J" first="James W" last="Kazura">James W. Kazura</name><affiliation wicri:level="2"><nlm:affiliation>Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Fleckenstein, Lawrence L" sort="Fleckenstein, Lawrence L" uniqKey="Fleckenstein L" first="Lawrence L" last="Fleckenstein">Lawrence L. Fleckenstein</name><affiliation wicri:level="4"><nlm:affiliation>Department of Pharmaceutical Sciences & Experimental Therapeutics, University of Iowa, Iowa City.</nlm:affiliation><orgName type="university">Université de l'Iowa</orgName><country>États-Unis</country><placeName><settlement type="city">Iowa City</settlement><region type="state">Iowa</region></placeName></affiliation></author><author><name sortKey="King, Christopher L" sort="King, Christopher L" uniqKey="King C" first="Christopher L" last="King">Christopher L. King</name><affiliation wicri:level="2"><nlm:affiliation>Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Center for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland</wicri:cityArea></affiliation></author></analytic><series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title><idno type="eISSN">1537-6591</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Albendazole (administration & dosage)</term><term>Albendazole (adverse effects)</term><term>Albendazole (pharmacokinetics)</term><term>Animals</term><term>Diethylcarbamazine (administration & dosage)</term><term>Diethylcarbamazine (adverse effects)</term><term>Diethylcarbamazine (pharmacokinetics)</term><term>Drug-Related Side Effects and Adverse Reactions (pathology)</term><term>Elephantiasis, Filarial (drug therapy)</term><term>Female</term><term>Filaricides (administration & dosage)</term><term>Filaricides (adverse effects)</term><term>Filaricides (pharmacokinetics)</term><term>Humans</term><term>Ivermectin (administration & dosage)</term><term>Ivermectin (adverse effects)</term><term>Ivermectin (pharmacokinetics)</term><term>Male</term><term>Middle Aged</term><term>Papua New Guinea</term><term>Parasitemia (drug therapy)</term><term>Pilot Projects</term><term>Serum (chemistry)</term><term>Single-Blind Method</term><term>Treatment Outcome</term><term>Wuchereria bancrofti (isolation & purification)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Albendazole (administration et posologie)</term><term>Albendazole (effets indésirables)</term><term>Albendazole (pharmacocinétique)</term><term>Animaux</term><term>Diéthylcarbamazine (administration et posologie)</term><term>Diéthylcarbamazine (effets indésirables)</term><term>Diéthylcarbamazine (pharmacocinétique)</term><term>Effets secondaires indésirables des médicaments (anatomopathologie)</term><term>Femelle</term><term>Filaricides (administration et posologie)</term><term>Filaricides (effets indésirables)</term><term>Filaricides (pharmacocinétique)</term><term>Filariose lymphatique (traitement médicamenteux)</term><term>Humains</term><term>Ivermectine (administration et posologie)</term><term>Ivermectine (effets indésirables)</term><term>Ivermectine (pharmacocinétique)</term><term>Jeune adulte</term><term>Mâle</term><term>Méthode en simple aveugle</term><term>Papouasie - Nouvelle-Guinée</term><term>Parasitémie (traitement médicamenteux)</term><term>Projets pilotes</term><term>Résultat thérapeutique</term><term>Sérum ()</term><term>Wuchereria bancrofti (isolement et purification)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Albendazole</term><term>Diethylcarbamazine</term><term>Filaricides</term><term>Ivermectin</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Albendazole</term><term>Diethylcarbamazine</term><term>Filaricides</term><term>Ivermectin</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Albendazole</term><term>Diethylcarbamazine</term><term>Filaricides</term><term>Ivermectin</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Albendazole</term><term>Diéthylcarbamazine</term><term>Filaricides</term><term>Ivermectine</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Effets secondaires indésirables des médicaments</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Serum</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Parasitemia</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Albendazole</term><term>Diéthylcarbamazine</term><term>Filaricides</term><term>Ivermectine</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Drug-Related Side Effects and Adverse Reactions</term></keywords><keywords scheme="MESH" qualifier="pharmacocinétique" xml:lang="fr"><term>Albendazole</term><term>Diéthylcarbamazine</term><term>Filaricides</term><term>Ivermectine</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Filariose lymphatique</term><term>Parasitémie</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Animals</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Papua New Guinea</term><term>Pilot Projects</term><term>Single-Blind Method</term><term>Treatment Outcome</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Méthode en simple aveugle</term><term>Papouasie - Nouvelle-Guinée</term><term>Projets pilotes</term><term>Résultat thérapeutique</term><term>Sérum</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Available treatments for lymphatic filariasis (LF) are limited in their longterm clearance of microfilaria from the blood. The safety and efficacy of a single-dose triple-drug therapy of the antifilarial drugs diethylcarbamazine (DEC), ivermectin (IVM), and albendazole (ALB) for LF are unknown.</div></front></TEI><affiliations><list><country><li>Papouasie-Nouvelle-Guinée</li><li>États-Unis</li></country><region><li>Iowa</li><li>Missouri (État)</li><li>Ohio</li></region><settlement><li>Iowa City</li></settlement><orgName><li>Université de l'Iowa</li></orgName></list><tree><country name="Papouasie-Nouvelle-Guinée"><noRegion><name sortKey="Thomsen, Edward K" sort="Thomsen, Edward K" uniqKey="Thomsen E" first="Edward K" last="Thomsen">Edward K. Thomsen</name></noRegion><name sortKey="Baea, Manasseh" sort="Baea, Manasseh" uniqKey="Baea M" first="Manasseh" last="Baea">Manasseh Baea</name><name sortKey="Lombore, Bart" sort="Lombore, Bart" uniqKey="Lombore B" first="Bart" last="Lombore">Bart Lombore</name><name sortKey="Maki, Elit" sort="Maki, Elit" uniqKey="Maki E" first="Elit" last="Maki">Elit Maki</name><name sortKey="Sanuku, Nelly" sort="Sanuku, Nelly" uniqKey="Sanuku N" first="Nelly" last="Sanuku">Nelly Sanuku</name><name sortKey="Satofan, Samson" sort="Satofan, Samson" uniqKey="Satofan S" first="Samson" last="Satofan">Samson Satofan</name><name sortKey="Siba, Peter M" sort="Siba, Peter M" uniqKey="Siba P" first="Peter M" last="Siba">Peter M. Siba</name></country><country name="États-Unis"><region name="Iowa"><name sortKey="Schmidt, Mark S" sort="Schmidt, Mark S" uniqKey="Schmidt M" first="Mark S" last="Schmidt">Mark S. Schmidt</name></region><name sortKey="Fleckenstein, Lawrence L" sort="Fleckenstein, Lawrence L" uniqKey="Fleckenstein L" first="Lawrence L" last="Fleckenstein">Lawrence L. Fleckenstein</name><name sortKey="Kazura, James W" sort="Kazura, James W" uniqKey="Kazura J" first="James W" last="Kazura">James W. Kazura</name><name sortKey="King, Christopher L" sort="King, Christopher L" uniqKey="King C" first="Christopher L" last="King">Christopher L. King</name><name sortKey="Weil, Gary J" sort="Weil, Gary J" uniqKey="Weil G" first="Gary J" last="Weil">Gary J. Weil</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26486704" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
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